Acquired immunodeficiency syndrome and lupus erythematosus are multisystem\ndiseases that can affect several organs and systems at different stages\nof disease evolution. Both diseases share common clinical manifestations,\nwhich may lead to diagnostic difficulties, especially at the onset of the disease.\nAnother additional challenge is when there is an association of the two pathologies.\nThe objective of this brief review is to describe the clinical manifestations\nof the diseases and to make considerations regarding the moment of\nonset of symptoms. Knowledge of these common manifestations and their\npeculiarities may alert clinicians to possible diagnoses and avoid errors in the\nevaluation and conduction of these patients.
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